DOI: 10.21276/ajptr
Mon, 22 Apr 2019

Floating Drug Delivery Systems: A Review

Swati Yadav*1, Saurabh Pandey 2, S.K Prajapati1

1.Institute of pharmacy, Bundelkhand University, Jhansi

2.ITS Paramedical (pharmacy) college, muradnagar, Ghaziabad


Most demanding route of administration is oral. Several times dosing of conventional drug delivery system to achieve effective therapeutic range is always abhorred by the patient. Demanding new approach to reduce the number of intake; leading to introduction of gastric retention concept. As most of drugs are absorbed in upper intestinal tract GI retention was base to it. The floating drug delivery system is an admirable approach to gastric retention. Aim of delineating this review on Floating Drug Delivery System was to stash up the recent literature with special cogitation toward principal mechanism to attain gastric retention, also including details of Floating Drug Delivery System such as Classification, Mechanism of work, Method of preparation, Aspect of characterisation, Different factors to be taken care during process of formulation. This review is loaded with data of previous work performed on Floating Drug Delivery System, which includes desirable point to solve, the queries regarding FDDS.

Keywords: Floating microspheres, Floating Drug Delivery System, Gastro Retention, bioavailability, Hydrodynamically Balanced Systems.

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