DOI: 10.21276/ajptr
Thu, 24 Jan 2019

Cubosomes: A Novel Approach for Delivery of Anticancer Drugs

Gehan Balata*1,2, Manna Amin1, Fawazya Alhalabi1, Sarah Alansari1

1. Faculty of pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia

2 Faculty of pharmacy, Zagazig University, Zagazig, Egypt


Cubosomes are bicontinuous cubic liquid crystalline phases formed by the self-assembly of polar lipids, monolein, in water. They offer unique physicochemical properties than the other common colloidal delivery systems such as liposomes and nanoparticles. The article reviews about definition of cubosomes, advantages and disadvantages, composition and different production and characterization techniques. Moreover, there is an emphasis on the importance of cubosomes for the effective delivery of anticancer drugs.

Keywords: Cubosomes; monolein; anticancer; production; characterization.


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