DOI: 10.21276/ajptr
Tue, 19 Mar 2019

Isolation, Recovery and Analysis of Active Drug From Formulation

Kumar Pratyush1* , Alpana Asnani 1,Priya Dule1, Prakash Helonde2

1. Priyadarshini J.L. College of Pharmacy, Electronic Building, Electronic zone, Hingna Road, Nagpur – 440016, Maharashtra.


Drugs are used in pharmaceutical formulation to serve the mankind and help them to maintain their Quality of Life. As per literature survey we found that there are a fair number of paper that explains the formulation of dosage form by certain drugs, but none of them with explaining the aspect of isolation and retrieving of the active drug from the dosage form. In the current study Paracetamol is taken as the active drug which is used to formulate the best batch of tablet and then the drug is retrieved back from the best found formulation by the help of specific solvent. This solvent was determined by trial of several combinations and the best selected results are mentioned. 96.24 % of the active agents were isolated by the help of selected solvent. The drug compatibility study was carried out by Fourier Transform Infrared spectroscopy (FT-IR) and the structure determination of the isolated active agent was carried out by the Nuclear Magnetic Resonance (NMR) results. The assay of isolated active agent was carried out by UV spectroscopy. All these analytical data helped to elucidate the structure of isolated active agent and was found similar to that of Paracetamol.

Keywords: Quality of Life, active agent, paracetamol, UV, FT-IR, NMR.

[PDF]   Viewed: 632   Downloaded: 73
  • Call for paper

    American Journal of PharmTech Research (AJPTR) is a peer-reviewed, bimonthly official international journal allowing access to abstracts and full-text.



  • Email & SMS Alerts

    Email/SMS alert system is one of the key features and gives update information about the submitted manuscript.


  • Article Statastics

    American Journal of PharmTech Research (AJPTR) provides unique facility for authors to know popularity of articles on basis of numbers of PDF download and views. It will display in tabulated format.

  • Online Submission

    American Journal of PharmTech Research (AJPTR) is one of the International open access journal devoted to various disciplines in science and technology.


web counter
web counter