<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Article Tag Suite 1.1//EN"
  "https://jats.nlm.nih.gov/publishing/1.1/JATS-journalpublishing1.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink"
         xmlns:mml="http://www.w3.org/1998/Math/MathML"
         article-type="research-article"
         xml:lang="en">
  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>American Journal of PharmTech Research</journal-title>
        <abbrev-journal-title abbrev-type="publisher">AJPTR</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub">2249-3387</issn>
      <publisher>
        <publisher-name>undefined</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">AJPTR013034</article-id>
      <title-group>
        <article-title>FORMULATION AND EVALUATION OF FAST DISSOLVING TABLET OF PIROXICAM</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Panwar</surname>
            <given-names>A. S.</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Nagori</surname>
            <given-names>V.</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Chauhan</surname>
            <given-names>J.</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Darwhekar</surname>
            <given-names>G. N.</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Jain</surname>
            <given-names>D. K.</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">College of pharmacy, IPS Academy, Rajendra nagar, A B Road, Indore, M.P.-452012, India</aff>
      <pub-date pub-type="epub" iso-8601-date="2011-10-01">
        <month>10</month>
        <day>01</day>
        <year>2011</year>
      </pub-date>
      <volume>1</volume>
      <issue>3</issue>
      <abstract>
        <p>  Piroxicam is a non-steroidal anti-inflammatory drug, classified in the Biopharmaceutics Drug Classification system as a Class II drug with low solubility and high permeability. It demonstrates a slow and gradual absorption via the oral route and has a long half-life of elimination, rendering a prolonged therapeutic action and a delayed onset of anti-inflammatory and analgesic effect. The basic objective of the present study is to formulate and evaluate the fast dissolving tablet of Piroxicam. Study proposes the use of a Sodium Satrch Glycolate (SSG) alone to prepare solid dispersion of piroxicam and comparison of its in-vitro dissolution with pure piroxicam. Fast Dissolving tablets can be prepared by conventional direct compression method using solid dispersion of superdisintegrants which shows rapid rate of disintegration. For better Hardness, less friability, faster wetting time and less moisture uptake combination of both MCC and Mannitol are required in the formulation.   Key Words: Fast dissolving tablet, Piroxicam, Sodium starch Glycolate (SSG)</p>
      </abstract>
      <kwd-group kwd-group-type="author">
        <kwd>Fast dissolving tablet</kwd>
        <kwd>Piroxicam</kwd>
        <kwd>Sodium starch Glycolate (SSG)</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <!-- Full article body not available in metadata-only JATS export. See PDF/HTML galley. -->
  </body>
  <back/>
</article>
