Zanthoxylum armatum is used mainly in the Indian system of medicine as carminative, stomachic, toothache, fever, dyspepsia and expelling roundworms. Essential oils of Z.armatum exhibited good antibacterial, antifungal and anthelmintics activities. A wide variety of chemical compounds including alkaloids, flavonoids, sterols, triterpenoids have been found in this plant. It contains volatile oil with active constituents such as linalool, limonene and ligan. Various studies indicated that it possesses antilarvicidal, antifungal, hepatoprotective, and allopathic properties. This Review has basic information about Z.anthoxylum armatum and its biological activities for further development in this field.