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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>American Journal of PharmTech Research</journal-title>
        <abbrev-journal-title abbrev-type="publisher">AJPTR</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub">2249-3387</issn>
      <publisher>
        <publisher-name>undefined</publisher-name>
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    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">AJPTR022148</article-id>
      <title-group>
        <article-title>Development and Validation of UV Spectroscopy method for Estimation of Ranalozine in bulk and its Pharmaceutical Formulation</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Ganji</surname>
            <given-names>Ramanaiah</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Ramachandran</surname>
            <given-names>D.</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Srinivas</surname>
            <given-names>G</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Gowardhane</surname>
            <given-names>Jayapal</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Rao</surname>
            <given-names>Purnachanda</given-names>
          </name>
          <xref ref-type="aff" rid="aff1"/>
        </contrib>
      </contrib-group>
      <aff id="aff1">Department of Chemistry, Acharya Nagarjuna University Nuzivid campus, Andhra Pradesh, India.</aff>
      <pub-date pub-type="epub" iso-8601-date="2012-04-01">
        <month>04</month>
        <day>01</day>
        <year>2012</year>
      </pub-date>
      <volume>2</volume>
      <issue>2</issue>
      <abstract>
        <p>  A rapid and sensitive UV-Visible spectroscopic method was developed for the estimation of Ranalozine in pure and its Pharmaceutical formulations. The method was validated as per International Conference on Harmonization [ICH] guidelines. The Ranalozine was monitored at 230nm with UV detection and there is interference of diluent at 230nm for Ranalozine. The method was linear (r2 =0.999) at concentration ranging from 12 to 40μg/ml, precise (intra-day relative standard deviation [RSD] and inter-day RSD values &lt; 1.0%), accurate (mean recovery = 100.2%), specific and robust. The results showed that the proposed method is suitable for the precise, accurate and rapid determination of Ranalozine in bulk, its capsule dosage forms. Key Words: Ranalozine, UV-Visible spectroscopy, Validation, Dosage form.</p>
      </abstract>
      <kwd-group kwd-group-type="author">
        <kwd>Ranalozine</kwd>
        <kwd>UV-Visible spectroscopy</kwd>
        <kwd>Validation</kwd>
        <kwd>Dosage form.</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
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