The Improvement in the nanotechnology brings revolutionary changes & helps in preparing the novel formulations. The proniosomes are solid colloidal particles which may be hydrated immediately before use to yield the aqueous niosome dispersions similar to those that are produced by more cumbersome conventional methods. These proniosomes minimize the problems of niosome physical stability such as leaking, aggregation & fusion provide additional convenience in dosing, transportation, storage & distribution. The proniosomes overcome the disadvantages involved with liposomal & niosomal drug delivery systems. This review focuses on different aspects of proniosome such as components , types, preparation, evaluation & applications.