Herbal medicinal plants are the gift of nature to the human beings. The present review is an effort to give a detail literature survey and discovering the hidden Marvels of Commiphora wightii also its remarkable health benefits in human beings. Worldwide Commiphora wightii is also known as Guggul is known for its anti-inflammatory property. Along with these it has many pharmacological activities like in the treatment of Rhematoid arthritis, fibrinolysis, weight management, Cardioprotective action, thyroid function regulation, antioxidant support and in metastatis Inhibition. It contains various chemical constituents like guggulsterones, guggulipid, commiphoric acid, Monoterpenoids, guggultetrols, Steroids, flavonoids, diterpenoids, sesquiterpenoids, triterpenes, lignans and various amino acids which contribute to various therapeutic property.