Coronary Artery Disease (CAD) remains a leading cause of bidity and mortality globally, necessitating a profound understanding of its intricate pathophysiology diagnostic methodologies, and innovative therapeutic approaches. This comprehensive review aims to synthesize the current knowledge surrounding CAD, providing a holistic perspective on its multifaceted aspects. So I decided to review on proliferating CAD Heart Disease in the Satara region. And I found that the major reasons behind increasing CAD cases are Obesity in adults and changed lifestyles. So for Preventing the Proliferating of Diabetes, some Preventing Measures are used That is Tobacco smoking is also associated with an increased risk of CAD Heart Disease and its complications, so smoking cessation can be an important preventive measure as well. And also maintain the cholesterol in body.