The present study was planned to evaluate the effect of Sitopaladi churna & a herbal preparation on cell mediated immunity: by haematological parameters & by phagocytic activity of polymorpho nuclear  (PMN) cells in rats. Effect of Sitopaladi churna (1000 mg/ kg), Decoction of  herbs(10 ml/ kg) containing Embelia ribes seeds, Cymbopogon citratus(lemon grass), Zingiber officinale (ginger), Ocimum Sanctum(tulsi) on cell mediated immunity was evaluated by haematological parameters and by studying phagocytic activity by PMN cells. Both & herbal preparations shown increased cellular immunity as compared to control. Both herbal preparations shown comparable results with Septilin syrup (marketed by Himalaya) which was used as positive control (P>0.05). The study demonstrates that herbal preparations used in this study trigger cell mediated  immunity.