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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>American Journal of PharmTech Research</journal-title>
        <abbrev-journal-title abbrev-type="publisher">AJPTR</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub">2249-3387</issn>
      <publisher>
        <publisher-name>undefined</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">AJPTR33030</article-id>
      <title-group>
        <article-title>Validated RP-HPLC Method for the Estimation of Cinacalcet in Bulk and Tablet Dosage form</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Tekula</surname>
            <given-names>Radhika</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Prakash</surname>
            <given-names>K. Vanitha</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Susena</surname>
            <given-names>S.</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>R.Tejaswini</surname>
            <given-names>R.Tejaswini</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date pub-type="epub" iso-8601-date="2013-06-01">
        <month>06</month>
        <day>01</day>
        <year>2013</year>
      </pub-date>
      <volume>3</volume>
      <issue>3</issue>
      <abstract>
        <p>A Simple, selective, accurate, precise and linear RP-HPLC method was developed and subsequently validated for estimation of cinacalcet in bulk &amp; tablet dosage form. Gradient elution at a flow rate of 0.8ml/min was used for separation of drugs in reversed-phase mode using Waters HPLC 22695 model on a INERTSIL ODS C18 column (150 x 4.6 mm; 5µ) at a ambient temperature. Mobile phase consisted of water: methanol: acetonitrile (20:60:20). The UV detection wavelength was 235nm 20 µl was injected. The retention time for cinacalcet was 3.7min. The percentage RSD for precision and accuracy of the method was found to be less than 2%. The % recovery was within the range between 99.73% and 99.85%. The method was validated as per the ICH guidelines. Key words: cinacalcet, RP-HPLC, validation  </p>
      </abstract>
      <kwd-group kwd-group-type="author">
        <kwd>cinacalcet</kwd>
        <kwd>RP-HPLC</kwd>
        <kwd>validation</kwd>
      </kwd-group>
    </article-meta>
  </front>
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