Hospital acquired infections are commonly associated with Methicillin Resistant Staphylococcus aureus infection and treating these infections with chemotherapy is very perilous. The augment of multidrug-resistant strains makes it necessary to discover new classes of antimicrobials and compounds that restrain their resistance mechanisms. In the past few decades, the search for new anti-infective agents has betrothed many research groups in the field of ethno pharmacology. Many focus on determining the antimicrobial activity of plant extracts found in folk medicine, essential oils or isolated compounds. There are a large number of species that have been and are still used as medicinal plants, particularly in folk medicine. In the present study, we analyse the possibility of essential oils as potential antimicrobial crude drugs as well as a source for natural compounds that act as new anti-infectious agents.