The objective of this study was to formulate and evaluate dispersible tablets of diltiazem HCl using direct compression method for enhanced patient compliance. Oro dispersible tablets prepared by using super disintegrants such as croscarmellose sodium, crospovidone, sodium starch glycolate. It was observed that all the formulations were acceptable with reasonable limits of standard required for oro dispersible tablets. It was concluded that dispersible tablets with enhanced dissolution rate can be made using selected super disintegrants.