High blood pressure is a major cause of various diseases such as stroke and high cholesterol. High cholesterol and cause a variety of deadly diseases. The aim of this study was to conclude if a reduction in serum lipoproteins, especially LDL cholesterol, is a preventive approach against  atherosclerosis. Phlebotomy has been a recommended method to reduce serum lipoprotein levels. As cholesterol affects the blood flow it can also impact cardiovascular fitness and sufferers may find that they get out of breath more easily or just generally feel less fit and healthy or more tired. The present study was conducted to investigate the effects of wet cupping on serum lipoprotein concentrations. In this case it is observed that cupping therapy may be an effective method of reducing LDL cholesterol in men and consequently may have a preventive effect against atherosclerosis.