A study of 90 cases of urinary tract infection in patients with diabetes mellitus has been presented with special reference to epidemiological aspects. A Prospective study was conducted in diabetes mellitus patients with symptomatic Urinary tract infection. This study revealed the incidence of urinary tract infection to be more common in females underlining the fact that females are more prone to infection (Male: Female — 1:2.3).The incidence of urinary infection was progressively higher with the duration of diabetes mellitus, with most infections occurring beyond 10 years of diabetes. Patients most commonly presented with fever, increased frequency of micturation and dysuria and were found to have pyrexia, dehydration and suprapubic tenderness as the commonest clinical signs.