Plants are potent biochemical factories and have been components of phytomedicine. Since time immemorial man is able to obtain from them a wondrous assortment of industrial chemicals. Plant-based natural constituents can be derived from any part of the plant like bark, leaves, flowers, roots, fruits, seeds, etc., which may contain active components. Sudan with its uniquely variable climatic conditions possesses a huge wealth of flora. Capparis decidua Family (Capparidaceae), Cyperus rotundus Family (Cyperaceae) and Tribulus terrestris Family (Zygophyllaceae) were used successfully in Sudanese folkloric medicine for treatment of inflammatory disorders.  The present review described Botanical description, biological activites and phytochemical profile of these three plants.