Achievement of patient medication adherence remains challenging in Type 2 Diabetes management particularly population belongs to villages in South India.The aim is to assess adherence to anti diabetic drug therapy and self-management practice among type-2 diabetic patient by using Morisky-8-Item Medication adherence questionnaire at a community pharmacy located in South Indian village.: The results of morisky based questionnaire shows almost 84.8% of the respondents belongs to low adherence (>2). 15.2% having medium adherence and none having high medication adherence. The reasons including duration of disease, economy, co-morbidities, short consultation of time, multiple drug therapy and poor patient-health care professional relationship. However, short consultation of time and poor patient healthcare relationship are potentially modifiable to improve medication adherence in patients with diabetes.