Ebola virus is responsible for several major commotion of hemorrhagic fever which results in high mortality which creats elevation in great public threat. However, the structural similarity of Ebola virus glycoprotein (GP) to retrovirus envelops has been recently allotted.[6] The development of pseudo type recombinant retroviral particle that can be used to define the various aspects related to Ebola virus biology. There is no any particular treatment for Ebola virus syndrome but it can be prevented. The FDA has permitted two medications, Zmapp and a RNA interference medication called TKM-Ebola18 to be utilized as a part of individuals tainted with Ebola under these projects amid the 2014 episode. This review article is emphasis on life cycle of Ebola, pathophysiology, sign & symptoms, test & diagnosis, risk factor, treatment & precautions.