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  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>American Journal of PharmTech Research</journal-title>
        <abbrev-journal-title abbrev-type="publisher">AJPTR</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="epub">2249-3387</issn>
      <publisher>
        <publisher-name>undefined</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">AJPTR56032</article-id>
      <title-group>
        <article-title>UV-AUC Method Development and Validation for Estimation of 1h, 1’-H-2, 2’-Bibenzimidazole Impurity in Telmisartan Bulk and Formulation</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Patil</surname>
            <given-names>Poonam P.</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Kasture</surname>
            <given-names>Veena S.</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Prakash</surname>
            <given-names>K. Vanitha</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date pub-type="epub" iso-8601-date="2015-12-01">
        <month>12</month>
        <day>01</day>
        <year>2015</year>
      </pub-date>
      <volume>5</volume>
      <issue>6</issue>
      <abstract>
        <p>The aim of present work was to develop an accurate, precise, reproducible and economical UV spectrophotometric method for estimation of 1H, 1’-H-2, 2’-Bibenzimidazole Impurity In Telmisartan Bulk and Formulation. This method was based on area under curve of UV spectrum between 235 to 254 nm and validated as per ICH guideline Q2 (R1). The method has followed linearity in the range of 5-30μg/ml. The value of correlation coefficient was 0.998. Satisfactory values of Percent relative standard deviation for the intra-day and inter-day precision indicated that method is precise. Results of the recovery studies (97.63% to 98.66 %) showed accuracy of the method. LOD and LOQ were calculated as 0.3221μg/ml and 0.9761 μg/ml, respectively. The developed method can be used for routine estimation of 1H, 1’-H-2, 2’-Bibenzimidazole Impurity In Telmisartan Bulk and Formulation.</p>
      </abstract>
      <kwd-group kwd-group-type="author">
        <kwd>Telmisartan</kwd>
        <kwd>UV spectrophotometry</kwd>
        <kwd>Area under curve</kwd>
        <kwd>Validation</kwd>
        <kwd>Impurity</kwd>
      </kwd-group>
    </article-meta>
  </front>
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