Generic drug versus branded drug is a general concept  this idea is come in our mind  because the cost of the medicines is a concern for the patients. Within India cost of medicines varies, by doing the survey of Jan Aushadhi Stores price. Government should distinct price printed on drug as they are much higher than they are sold on whole sell price. Further survey was conducted for following target groups and individuals. The groups are Literate population, Common public  and Practicing Pharmacists. The different sets of questionnaire were prepared for each group and survey was conducted. Even if generic medicines are going to be made available free of cost at the government hospitals. The war of prices between branded and generic may not stop. More stringent rules and regulation are required for making the drugs available at reasonable cost for the masses. For the benefit of the patients, if pharmacist needs to change a brand for generic medicine, should be permitted by law. Awareness, knowledge and preference of medication.