Ferulic acid (4-hydroxy-3-methoxy cinnamic acid) isolated from the aerial parts of Cansjera rheedii J.Gmelin (Opiliaceae) has been tested for its antimicrobial activity The antimicrobial activity have been studied with ferulic acid  against Stapylococcus aureus, Bacillus substilis, Escherichia coli, Salmonilla paratyphi, Candida albicans, Aspergillus fumigates which gave significant results of activity against Ciprofloxacin & Clotrimazole as standards.