Synthesis & antibacterial activities of 1-phenyl-5-(1H-pyrrol-1yl)-1H-pyrazole-4-carboxilic acid N&#146;-acyl hydrazides

Laxmikant S Pavase; Prashant P Dixit; B R Chaudhari; Dhananjay V Mane; Laxmikant S Pavase; Prashant P Dixit; B R Chaudhari; Dhananjay V Mane

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Synthesis & antibacterial activities of 1-phenyl-5-(1H-pyrrol-1yl)-1H-pyrazole-4-carboxilic acid N-acyl hydrazides

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Published in June 2015 Issue 3 (Vol. 5, Issue 3, 2015)

Synthesis & antibacterial activities of 1-phenyl-5-(1H-pyrrol-1yl)-1H-pyrazole-4-carboxilic acid N-acyl hydrazides - Issue cover

Keywords

phenyl hydrazine pyrazole-4-carboxilic acid Clauson-Kass procedure hydrazide antibacterial activity

Abstract

A Novel series of 1-phenyl-5-(1H-pyrrol-1yl)-1H-pyrazole-4-carboxilic acid hydrazide derivatives were prepared by a 4 step course of action starting with Phenyl Hydrazine and 2-(1-ethoxyethylidine)malononitrile, with good yields and simple reaction condition. Synthesized compounds were test for their antibacterial activities. The structures were confirmed by ES-MS, NMR analysis.

Authors (4)

Laxmikant S Pavase

Department of Chemistry, Dr. B...Department of Chemistry, Dr. Babasaheb Ambedkar Ma...Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University,...Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad Maharashtra, India...

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Prashant P Dixit

Department of Microbiology, Dr...Department of Microbiology, Dr. Babasaheb Ambedkar...Department of Microbiology, Dr. Babasaheb Ambedkar Marathwada Universi...Department of Microbiology, Dr. Babasaheb Ambedkar Marathwada University, Sub campus, Osmanabad, Mah...

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B R Chaudhari

JES's Z B Patil college, Dhule...JES's Z B Patil college, Dhule. Maharashtra.JES's Z B Patil college, Dhule. Maharashtra.JES's Z B Patil college, Dhule. Maharashtra.

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Dhananjay V Mane

Department of Chemistry, Dr. B...Department of Chemistry, Dr. Babasaheb Ambedkar Ma...Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University,...Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad Maharashtra, India...

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Published in:

June 2015 Issue 3 (Vol. 5, Issue 3, 2015)

Article ID:

AJPTR53036

Paper ID:

AJPTR-01-002569

Published Date:

2015-06-01

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S, L., & P, P. & R, B. & V, D. (2015). Synthesis & antibacterial activities of 1-phenyl-5-(1H-pyrrol-1yl)-1H-pyrazole-4-carboxilic acid N-acyl hydrazides. American Journal of PharmTech Research, 5(3), xx-xx. https://ajptr.com/articles/AJPTR53036

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Synthesis & antibacterial activities of 1-phenyl-5-(1H-pyrrol-1yl)-1H-pyrazole-4-carboxilic acid N-acyl hydrazides

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