Comparative Evaluation of Anti Acne formulations

The most common skin disease, acne vulgaris is inflammatory in nature and is caused by bacteria P. acne and S.epidermidis. The present study was carried out to formulate separately the topical anti acne formulations of coriander aqueous extract and its oil using carbopol as gelling agent and to compare them with marketed formulation. The developed formulations were compared for antimicrobial studies, viscosity and spreadibility, kinetics of release, in-vitro diffusion and permeation. The antibacterial study was conducted by well diffusion method. The permeation of the developed formulations was more than that of marketed one. The marketed formulation was found to be less effective than the coriander formulation.