Solvent-Free and Conventional Approach to the Synthesis of Indazole Derivatives through Cyclohexenone and Their Antibacterial Activity

Q: Who are the authors of this article and where was it published?

Pranita Sadaphale, L.J.Paliwal, M.B.Bagade. Published in American Journal of PharmTech Research, Vol. 4, No. 6, (2014).

Q: Is the full text of this article freely available?

Yes. This article is published open access under CC BY 4.0. The full text and PDF can be downloaded free of charge.

Q: What are the key topics covered in this article?

1-napthaldehyde, chalcones, cyclohexenone, indazole, antibacterial, microwave irradiation..

Pranita Sadaphale; L.J.Paliwal; M.B.Bagade

Published

Solvent-Free and Conventional Approach to the Synthesis of Indazole Derivatives through Cyclohexenone and Their Antibacterial Activity

Pranita Sadaphale

,

L.J.Paliwal

,

M.B.Bagade

Published in December 2014 Issue 6 (Vol. 4, Issue 6, 2014)

Solvent-Free and Conventional Approach to the Synthesis of Indazole Derivatives through Cyclohexenone and Their Antibacterial Activity - Issue cover

Keywords

1-napthaldehyde chalcones cyclohexenone indazole antibacterial microwave irradiation.

Abstract

Microwave assisted solvent free synthesis of cyclohexenone and indazole derivatives were carried out by chalcones derived from different acetophenones and 1-naphthaldehyde. Structures of the compounds have been characterized by IR, 1H NMR, Mass spectrometry and elemental analysis. All the synthesized indazole derivatives were screened for antibacterial activity and are found to posses moderate to good activity against some species of bacteria.

Authors (3)

Pranita Sadaphale

Department of Chemistry, Rasht...Department of Chemistry, Rashtrasant Tukadoji Maha...Department of Chemistry, Rashtrasant Tukadoji Maharaj, Nagpur Universi...Department of Chemistry, Rashtrasant Tukadoji Maharaj, Nagpur University, Nagpur-440 033 (India).

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L.J.Paliwal

Department of Chemistry, Seth ...Department of Chemistry, Seth Kesarimal Porwal Col...Department of Chemistry, Seth Kesarimal Porwal College, Kamptee-441 00...Department of Chemistry, Seth Kesarimal Porwal College, Kamptee-441 002 (India).

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M.B.Bagade

Department of Chemistry, Seth ...Department of Chemistry, Seth Kesarimal Porwal Col...Department of Chemistry, Seth Kesarimal Porwal College, Kamptee-441 00...Department of Chemistry, Seth Kesarimal Porwal College, Kamptee-441 002 (India).

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Article Information

Published in:

December 2014 Issue 6 (Vol. 4, Issue 6, 2014)

Article ID:

AJPTR46040

Paper ID:

AJPTR-01-002452

Pages:

1-10

Published Date:

2014-12-01

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Citation Format

Sadaphale, P., L.J.Paliwal, & M.B.Bagade (2014). Solvent-Free and Conventional Approach to the Synthesis of Indazole Derivatives through Cyclohexenone and Their Antibacterial Activity. American Journal of PharmTech Research, 4(6), 1-10. https://ajptr.com/articles/AJPTR46040