Preparation and Characterization of Amlodipine Besylate Polymorphs

The objective of the present work was to make different crystal forms of Amlodipine besylate. It was planned to prepare crystal forms using solvents of varying polarity and by change of phase and it was extended to characterize the prepared crystal forms using techniques like Scanning electron microscopy, IR spectroscopy, and Differential scanning calorimetry and/or X-ray diffractometry. Based on above these studies Amlodipine besylate pure was exisisted as Amlo-I, Amlo-II, Amlo –III and Amlo-IV forms were different in size and shape.