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e-ISSN: 2249-3387
American Journal of PharmTech Research

American Journal of PharmTech Research

Published

Friedel-Craft Acylation of Phenols in 1-Ethyl-3-Methylimidazolium Tetrachloroaluminate Ionic Liquid.

Published in October 2018 Issue 5 (Vol. 8, Issue 5, 2018)

Friedel-Craft Acylation of Phenols in 1-Ethyl-3-Methylimidazolium Tetrachloroaluminate Ionic Liquid. - Issue cover

Abstract

Through this review we would like to introduce clean and efficient method of most conventional Friedel-Craft acylation of phenols using Ionic liquid. This method has best results of acylated phenols in terms of quality and yields are concerned. The Friedel-Craft acylation is an everyday applicable industrial synthesis. Phenols are dihydric, trihydric as well as monohydric hydrocarbons used to undergo acylation. Acetyl chloride is best suitable reagent for aromatic C-acylation. Ionic liquid [EMIM][AlCl4] has best solvation and catalytic effect in the reaction. Key Word: Friedel-Craft Acylation, Phenols, Ionic liquid [EMIM][AlCl4], Acetyl Chloride  

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Authors (2)

Mahendra Sawant

Department of Chemistry, Siddh...

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Nandkishor Chandan

Department of Chemistry, Siddh...

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Article Information

AJPTR85009

AJPTR-01-001509

1-7

2018-10-01

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How to Cite

Sawant, M., & Chandan, N. (2018). Friedel-Craft Acylation of Phenols in 1-Ethyl-3-Methylimidazolium Tetrachloroaluminate Ionic Liquid.. American Journal of PharmTech Research, 8(5), 1-7. https://doi.org/10.46624/ajptr.2018.v8.i5.009

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