Jagdish D. Shukla
Author Profile
Department of Chemistry, Maulana Azad college, Dr. Rafiq Zakaria Campus, Rauza Baugh, Aurangabad (M.S.), INDIA.
1
Publications
1
Years Active
2
Collaborators
6
Citations
Publications by Jagdish D. Shukla
1 publication found • Active 2015-2015
2015
1 publicationSynthesis and Pharmacological Evaluation of Novel 1-(2, 6-Difluorobenzyl)-1h-1, 2, 3-Triazole Derivatives for Cns Depressant and Anticonvulsant Profile
with Pathan Md. Arif Ali Khan, Keshav Deo
6/1/2015
A series of 1-(2, 6-difluorobenzyl)-1H-1, 2, 3-triazole (5a-d and 7a-d) were synthesized and evaluated for CNS depressant and anticonvulsant activities by photoactometer, rotarod and pentylene tetrazole induced convulsion method respectively in Swiss albino mice. Diazepam was used as a standard drug. Out of the 8 compounds tested, compounds (5b, 7a and 7b) were showed the CNS depressant activity comparable to that of diazepam at a dose of 5 mg/kg. The active members of the series (5b, 7a and 7b) were selected for anticonvulsant activity study.
Author Statistics
Total Publications:1
Years Active:1
First Publication:2015
Latest Publication:2015
Collaborators:2
Citations:6
Collaborators