Rajib Lochan Maharana

Alzheimer’s disease is the most prevalent form of dementia. Neuropathogenesis is proposed to be a result of the accumulation of amyloid β- peptides in the brain together with oxidative stress mechanisms and neuroinflammation. Drugs effective in Alzheimer’s disease (AD) should have several aims: to improve the cognitive impairment, control the behavioral and neurological symptoms, delay the progression of the disease, and prevent the onset. This review discusses the molecular mechanism of Alzheimer’s disease with a focus on the different agents those are inhibit the progression of the disease and improved patients condition and status.. Key words: Alzheimer’s disease, β-amyloid, Tacrine, Rivastigmine