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e-ISSN: 2249-3387
American Journal of PharmTech Research

American Journal of PharmTech Research

Published

New Analytical Methods for the Determination of Two Gliptin Drugs In Pharmaceutical Formulations and Urine Samples

Published in February 2020 Issue 1 (Vol. 10, Issue 1, 2020)

New Analytical Methods for the Determination of Two Gliptin Drugs In Pharmaceutical Formulations and Urine Samples - Issue cover

Abstract

New ion – associate complexes of the two gliptin drugs, vildagliptin and saxagliptin were precipitated with tetraiodometrcurate and ammonium reineckate and the excess unreacted metal complex was determined. New methods were given for the determination of these drugs in pure solutions, pharmaceutical formulations and urine samples using atomic absorption and atomic emission spectrometry. The drugs can be determined by the afford methods  in the ranges 0.68 – 74.69 and 0.70 – 77.42 μg / ml for vildagliptin and saxagliptin, respectively.

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Article Information

AJPTR101004

AJPTR-01-001883

1-13

2020-02-01

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How to Cite

Khalil, S., Bushara, A., & Farag, H. (2020). New Analytical Methods for the Determination of Two Gliptin Drugs In Pharmaceutical Formulations and Urine Samples. American Journal of PharmTech Research, 10(1), 1-13. https://doi.org/10.46624/ajptr.2020.v10.i1.004

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