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Quantitative determination of Domperidone and Ranitidine in combined dosage form by FT-IR spectroscopy

P. Ravi Prasad
,
K. Bhuvaneswari
,
Murarilal
,
K. Rajani

Published in August 2012 Issue 4 (Vol. 2, Issue 4, 2012)

Quantitative determination of Domperidone and Ranitidine in combined dosage form by FT-IR spectroscopy - Issue cover

Keywords

FT-IRRanitidineDomperidonecombined dosage form.

Abstract

  A simple and rapid method has been developed for the quantification of Domperidone (DMP) and Ranitidine (RAN) through FT-IR in combined dosage form. The method involves the measurement of peaks of amine (-NH) at 1620 cm-1 (RAN) and carbonyl group (C=O) at 1717 cm-1 (DMP). The method was validated for pharmaceuticals in tablet form and found to be precise with high recovery levels (>99%). Key words: FT-IR, Ranitidine, Domperidone, combined dosage form.

Authors (4)

P. Ravi Prasad

Analytical Chemistry Division,...

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K. Bhuvaneswari

Analytical Chemistry Division,...

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Murarilal

Analytical Chemistry Division,...

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K. Rajani

Analytical Chemistry Division,...

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Article Information

Published in:

August 2012 Issue 4 (Vol. 2, Issue 4, 2012)

AJPTR024299

AJPTR-01-002216

2012-08-01

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How to Cite

Ravi, P., & Bhuvaneswari & Murarilal & Rajani (2012). Quantitative determination of Domperidone and Ranitidine in combined dosage form by FT-IR spectroscopy. American Journal of PharmTech Research, 2(4), xx-xx. https://ajptr.com/articles/AJPTR024299

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