Pharmacological
Explore 2 research publications tagged with this keyword
Publications Tagged with "Pharmacological"
2 publications found
2026
1 publicationPhytochemical Screening and Evaluation of Banyan Tree (Ficus benghalensis) Aerial Root Extract for Anti-Inflammatory Activity in Gingivitis
The aerial root of the Banyan Tree was tested and assessed for its anti-inflammatory effects in the case of Gingivitis.The collection and identification of the plant material involved gathering the main aerial parts of the Banyan tree from a local area.The outer surface of the aerial root of *Ficus benghalensis* is gray in color, while the cut surface is reddish-brown and rough, with longitudinal and transverse cracks, as well as rows of lenticels.The fracture surface shows a fibrous, tough bark, and the wood portion is short.The anatomy of the roots showed a well-defined secondary growth pattern.The physiochemical properties of *Ficus benghalensis* were analyzed, including loss on drying, ash values, and extractive values.The aqueous extract was found to contain flavonoids, phenolics, saponins, proteins, and carbohydrates.The total alkaloid content was calculated in terms of atropine equivalent (mg/100mg) based on a calibration curve.The total flavonoid content in the test samples was determined using a calibration plot (Y = 0.0162x + 0.0044, R² = 0.999) and expressed as milligrams of quercetin equivalent (QE) per gram of dried plant material.Group III, which received the extract (EMM) at a dose of 400 mg/kg from the aerial roots of *Ficus benghalensis*, showed a higher percentage of paw edema inhibition compared to Group II (ESM) and Group IV (EDM) that received other extracts of the same plant.However, both groups treated with the extract exhibited lower anti-inflammatory activity than the positive control.
2014
1 publicationA Review On Pharmacognostical, Phytochemical and Pharmacological Potentials of Kalanchoe pinnata (Crassulaceae)
Kalanchoe pinnata (Family: Crassulaceae) is an important plant which has many traditional medicinal uses. The main objective of this literature review was to give advance information for the drug discovery research for K. pinnata. It was found that this plant showed various pharmacological activities such as anthelmentic, immunosuppressive, wound healing, hepatoprotective, antinociceptive, anti-inflammatory, antidiabetic, nephroprotective, antioxidant activity, antimicrobial activity, analgesic, anticonvulsant, neuropharmacological and antipyretic. Anthelmentic activity was found due to the presence of tannins of the extract of K. pinnata and steroid glycosides such as bufadienolide showed wound healing activity. It was also found that the different flavonoids, polyphenols, triterpenoids and other chemical constituents of the plant were responsible for the antinociceptive, antiinflammatory and antidiabetic properties. Quercetin had a marked protective effect on cadmiuminduced nephrotoxicity and possessed potent oral efficacy against cutaneous leishmaniasis. The two new novel flavonoids such as 5Methyl 4, 5, 7 trihydroxyl flavone and 4, 3, 5, 7 tetrahydroxy 5-methyl 5 Ipropenamine anthocyanidines could be responsible for the antimicrobial activity of K. pinnata. Five bufadienolides (1-5) isolated from the leaves of K. pinnata were potential cancer chemopreventive agents. Quercitrin, a flavonoid, is a critical component of K. pinnata extract against an extreme allergic reaction. This literature review gave the evidence based information regarding the pharmacognostical, phytoconstituents and pharmacological activity of the medicinal plant, K. pinnata which could help researchers for more advanced qualitative research.
